F.A. Davis Company

Build the foundation you need to understand the science of genetics and its growing role in the diagnosis and treatment of diseases and disorders. Two experts in the field present the biological, psychological, and social implications of genetic influences in health care in an easy-to-read and -understand style.

Inside, you’ll find the thorough coverage and clinical examples you need to understand the basis of genetic inheritance, the influence of somatic and germline mutations, the multifactorial relationship of gene-environment interactions, and the foundation of ethical behavior in providing comprehensive genetic nursing care. It’s perfect for both stand-alone courses or integrated into courses across the curriculum.

• Includes information on how to perform beginning genetic assessments, including the development of a three generation pedigree for identification of genetic risks.
• Focuses on the genetic factors influencing the most common health problems.
• Organizes disorders using a lifespan approach.
• Integrates online resources including National Human Genome Research Institute, Science Behind the News, and Genetest to help visualize the content.
• Features content on clinical disorders, genetic testing, ethics, genetic discrimination, and the roles of healthcare professionals
• Uses a consistent organization in every chapter that includes case presentations, clinical manifestations/assessment findings, interpretation of laboratory data, risks, potential complications, and nursing care needs.

1. Basic Concepts from Molecular Genetics
   1. DNA Structure and Function
   2. Protein Synthesis
   3. Genetic Influences on Cell Growth, Cell Differentiation, and Gametogenesis
2. Gene Expression
   4. Patterns of Inheritance
   5. Chromosomal and Mitochondrial Inheritance and Disorders
   6. Family History and Pedigree Construction
   7. Congenital Anomalies, Basic Dysmorphology, and Genetic Assessment
3. Genomic Health Problems Across the Lifespan
   8. Enzyme and Collagen Disorders
   9. Common Childhood-Onset Genetic Disorders
   10.  Common Adult-Onset Genetic Disorders
4. Genomic Influences on Selected Complex Health Problems
   11. Cardiovascular Disorders
   12. The Genetics of Cancer
   13. Genetic Contributions to Psychiatric and Behavioral Disorders
5. Genomics and Disease Management
   14. Genetic and Genomic Testing
   15. Assessing Genomic Variation in Drug Response
   16. Health Professionals and Genomic Care
6. Global Genomic Issues
   17. Financial, Legal, Ethical, and Social Considerations
   18. Genetic and Genomic Variation
7. Appendices
   1. Genetic Competencies Identified by the American Association of Colleges of Nursing
   2. Core Competencies from the National Coalition for Health Professional Education in Genetics (NCHPEG)
   3. Essentials for Genetic and Genomic Nursing: Competencies, Curricula Guideline, and Outcome Indicators, 2nd Edition
   4. Genetic Organizations and Support Groups
   5. Selected Educational Websites